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Article

The Influenza A Virus Genotype Determines the Antiviral Function of NF-κB.

Journal of virology - 1 Sept 2016

Dam Sharmistha, Kracht Michael, Pleschka Stephan, Schmitz M Lienhard

Abstract excerpt

UNLABELLED: The role of NF-κB in influenza A virus (IAV) infection does not reveal a coherent picture, as pro- and also antiviral functions of this transcription factor have been described. To address this issue, we used clustered regularly interspaced short palindromic repeat with Cas9 (CRISPR-Cas9)-mediated genome engineering to generate murine MLE-15 cells lacking two essential components of the NF-κB pathway....

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Identifiers

PMID: 27356900
DOI: 10.1128/JVI.00946-16
PMCID: PMC4988167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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