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Article

An unbiased genetic screen reveals the polygenic nature of the influenza virus anti-interferon response.

Journal of virology - 1 May 2014

Pérez-Cidoncha Maite, Killip Marian J, Oliveros Juan C, Asensio Víctor J, Fernández Yolanda, Bengoechea José A, Randall Richard E, Ortín Juan

Abstract excerpt

UNLABELLED: Influenza A viruses counteract the cellular innate immune response at several steps, including blocking RIG I-dependent activation of interferon (IFN) transcription, interferon (IFN)-dependent upregulation of IFN-stimulated genes (ISGs), and the activity of various ISG products; the multifunctional NS1 protein is responsible for most of these activities. To determine the importance of other viral...

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Identifiers

PMID: 24574395
DOI: 10.1128/JVI.00014-14
PMCID: PMC3993829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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