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Article

SNPs in NRXN1 and CHRNA5 are associated to smoking and regulation of GABAergic and glutamatergic pathways.

Pharmacogenomics - 1 Jul 2016

Pérez-Rubio Gloria, Pérez-Rodríguez Martha E, Fernández-López Juan Carlos, Ramírez-Venegas Alejandra, García-Colunga Jesús, Ávila-Moreno Federico, Camarena Angel, Sansores Raúl H, Falfán-Valencia Ramcés

Abstract excerpt

AIM: To identify genetic variants associated with greater tobacco consumption in a Mexican population. PATIENTS & METHODS: Daily smokers were classified as light smokers (LS; n = 742), heavy smokers (HS; n = 601) and nonsmokers (NS; n = 606). In the first stage, a genotyping microarray that included 347 SNPs in CHRNA2-CHRNA7/CHRNA10, CHRNB2-CHRNB4 and NRXN1 genes and 37 ancestry-informative markers was used to...

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Source

Identifiers

PMID: 27355804
DOI: 10.2217/pgs-2016-0020

Genes

NRXN1
CHRNA5
GABRB2
GRID2
CHRNA10
CHRNA2
CHRNA7
CHRNB2
CHRNB4
GABRA4
GABRG1
GRIA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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