Article
Glutamate and synaptic plasticity systems and smoking behavior: results from a genetic association study.
PloS one - 1 Jan 2012
dos Santos Vanessa Argondizo, Chatkin Jose Miguel, Bau Claiton Henrique Dotto, Paixão-Côrtes Vanessa Rodrigues, Sun Ye, Zamel Noe, Siminovitch Katherine
Abstract excerpt
Smoking behavior is a multifactorial phenotype with significant heritability. Identifying the specific loci that influence smoking behavior could provide important etiological insights and facilitate the development of treatments to further reduce smoking related mortality. Although several studies pointed to different candidate genes for smoking, there is still a need for replication especially in samples from...
Topics
- Adult
- Brazil
- Female
- Genetics, Population
- Genome-Wide Association Study
- Glutamates
- Humans
- Male
- Middle Aged
- Neuronal Plasticity
- Polymorphism, Single Nucleotide
- Smoking