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Article

Novel role of ASC as a regulator of metastatic phenotype.

Cancer medicine - 1 Sept 2016

Okada Nagisa, Fujii Chifumi, Matsumura Tomio, Kitazawa Masato, Okuyama Ryuhei, Taniguchi Shun'ichiro, Hida Shigeaki

Abstract excerpt

Disorders of cytoskeletal remodeling and signal transduction are frequently involved in cancer progression. In particular, apoptosis-associated speck-like protein containing a caspase-recruitment domain (ASC) has been reported a proapoptotic molecule that is epigenetically silenced in several human cancers. ASC is a well-characterized adaptor protein involved in the formation of multiprotein oligomers, called...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27350283
DOI: 10.1002/cam4.800
PMCID: PMC5055161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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