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Article

NLRP3 Inflammasome Activation in Cancer: A Double-Edged Sword

8 Jul 2020

Abstract excerpt

Inflammation is involved in tumor development and progression as well as antitumor response to therapy. In the past decade, the crosstalk between inflammation, immunity, and cancer has been investigated extensively, which led to the identification of several underlying mechanisms and cells involved. The formation of inflammasome complexes leads to the activation of caspase-1, production of interleukin (IL)-1β,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32733479
DOI: 10.3389/fimmu.2020.01444

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