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Identifying and characterizing recently transmitted viruses

5 May 2010

Abstract excerpt

PURPOSE OF REVIEW: Improvements in sequencing approaches and robust mathematical modeling have dramatically increased information on viral genetics during acute infection with HIV and simian immunodeficiency virus, providing unprecedented insight into viral transmission and viral/immune interactions. RECENT FINDINGS: Overall viral genetic diversity is reduced significantly during mucosal transmission. Remarkably,...

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PMID: 20543609
DOI: 10.1097/coh.0b013e32833a0b9b

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