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Article

Mutational networks of escape from transmitted HIV-1 infection.

PloS one - 1 Jan 2020

Akand Elma H, Maher Stephen J, Murray John M

Abstract excerpt

Human immunodeficiency virus (HIV) is subject to immune selective pressure soon after it establishes infection at the founder stage. As an individual progresses from the founder to chronic stage of infection, immune pressure forces a history of mutations that are embedded in envelope sequences. Determining this pathway of coevolving mutations can assist in understanding what is different with the founder virus...

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Share to Computational Biology
Share to env Gene Products, Human Immunodeficiency Virus
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp160

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Identifiers

PMID: 33284837
DOI: 10.1371/journal.pone.0243391
PMCID: PMC7721145

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