Article
Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs.
Nucleic acids research - 14 Oct 2016
Yip W S Vincent, Shigematsu Hideki, Taylor David W, Baserga Susan J
Abstract excerpt
Ribosomal RNA (rRNA) modifications are essential for ribosome function in all cellular organisms. Box C/D small (nucleolar) ribonucleoproteins [s(no)RNPs] catalyze 2'-O-methylation, one rRNA modification type in Eukarya and Archaea. Negatively stained electron microscopy (EM) models of archaeal box C/D sRNPs have demonstrated the dimeric sRNP (di-sRNP) architecture, which has been corroborated by nuclear magnetic...
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