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Article

Identification and structural analysis of the Schizosaccharomyces pombe SMN complex.

Nucleic acids research - 21 Jul 2021

Veepaschit Jyotishman, Viswanathan Aravindan, Bordonné Rémy, Grimm Clemens, Fischer Utz

Abstract excerpt

The macromolecular SMN complex facilitates the formation of Sm-class ribonucleoproteins involved in mRNA processing (UsnRNPs). While biochemical studies have revealed key activities of the SMN complex, its structural investigation is lagging behind. Here we report on the identification and structural determination of the SMN complex from the lower eukaryote Schizosaccharomyces pombe, consisting of SMN, Gemin2, 6,...

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Identifiers

PMID: 33754639
DOI: 10.1093/nar/gkab158
PMCID: PMC8287938

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