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Article

C/D box sRNA-guided 2'-O-methylation patterns of archaeal rRNA molecules.

BMC genomics - 22 Aug 2015

Dennis Patrick P, Tripp Vanessa, Lui Lauren, Lowe Todd, Randau Lennart

Abstract excerpt

BACKGROUND: In archaea and eukaryotes, ribonucleoprotein complexes containing small C/D box s(no)RNAs use base pair complementarity to target specific sites within ribosomal RNA for 2'-O-ribose methylation. These modifications aid in the folding and stabilization of nascent rRNA molecules and their assembly into ribosomal particles. The genomes of hyperthermophilic archaea encode large numbers of C/D box sRNA...

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Identifiers

PMID: 26296872
DOI: 10.1186/s12864-015-1839-z
PMCID: PMC4644070

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Source receipt: pubmed, retrieved 7 Sept 2026.

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