Article

Visualising formation of the ribosomal active site in mitochondria

2021-03-20

Abstract excerpt

<h4>Summary</h4> Ribosome assembly is an essential and complex process that is regulated at each step by specific biogenesis factors. Using cryo-electron microscopy, we identify and order major steps in the formation of the highly conserved peptidyl transferase centre (PTC) and tRNA binding sites in the large subunit of the human mitochondrial ribosome (mitoribosome). The conserved GTPase GTPBP7 regulates the fol...

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Literature Corpus work: dc8d35d8-2ace-5b98-b45b-af3761fea0ab
DOI: 10.1101/2021.03.19.436169

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