Article
Exploration of pairing constraints identifies a 9 base-pair core within box C/D snoRNA-rRNA duplexes.
Journal of molecular biology - 8 Jun 2007
Chen Chun-Long, Perasso Roland, Qu Liang-Hu, Amar Laurence
Abstract excerpt
2'-O-ribose methylation of eukaryotic ribosomal RNAs is guided by RNA duplexes consisting of rRNA and box C/D small nucleolar (sno)RNA sequences, the methylated sites invariably mapping five positions apart from the D box. Here we have analyzed the RNA duplex pairing constraints by investigating the features of 415 duplexes from the fungus, plant and animal kingdoms, and the evolution of those duplexes within the...
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