Article
The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation.
RNA (New York, N.Y.) - 1 Jun 2006
Zhang Xinxin, Champion Erica A, Tran Elizabeth J, Brown Bernard A, Baserga Susan J, Maxwell E Stuart
Abstract excerpt
Archaeal box C/D sRNAs guide the methylation of specific nucleotides in archaeal ribosomal and tRNAs. Three Methanocaldococcus jannaschii sRNP core proteins (ribosomal protein L7, Nop56/58, and fibrillarin) bind the box C/D sRNAs to assemble the sRNP complex, and these core proteins are essential for nucleotide methylation. A distinguishing feature of the Nop56/58 core protein is the coiled-coil domain,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
