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Article

Polymorphisms of multiple genes involved in NER pathway predict prognosis of gastric cancer.

Oncotarget - 26 Jul 2016

Liu Jingwei, Deng Na, Xu Qian, Sun Liping, Tu Huakang, Wang Zhenning, Xing Chengzhong, Yuan Yuan

Abstract excerpt

Nucleotide excision repair (NER) is a versatile system that repairs various DNA damage. Polymorphisms of core NER genes could change NER ability and affect gastric cancer (GC) prognosis. We systematically analyzed the association between 43 SNPs of ten key NER pathway genes (ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, ERCC8, XPA, XPC, and DDB2) and overall survival (OS) of 373 GC patients in Chinese. Genotyping was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27340861
DOI: 10.18632/oncotarget.10173
PMCID: PMC5217006

Genes

DDB2
ERCC1
ERCC2
ERCC5
ERCC6
ERCC3
ERCC4
ERCC8
XPA
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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