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Article

Potentially functional variants in the core nucleotide excision repair genes predict survival in Japanese gastric cancer patients.

Carcinogenesis - 1 Sept 2014

Li Yangkai, Liu Zhensheng, Liu Hongliang, Wang Li-E, Onodera Hisashi, Suzuki Akihiro, Suzuki Koyu, Wadhwa Roopma, Elimova Elena, Sudo Kazuki, Shiozaki Hironari, Estrella Jeannelyn, Lee Ju-Seog, Song Shumei, Tan Dongfeng, Ajani Jaffer A, Wei Qingyi

Abstract excerpt

Functional genetic variants of DNA repair genes may alter the host DNA repair capacity, and thus influence efficiency of therapies. We genotyped eight potentially functional single nucleotide polymorphisms (SNPs) in genes (i.e. ERCC1, XPA, XPC, XPD and XPG) involved in the nucleotide excision repair (NER) pathway in 496 Japanese gastric cancer patients, and assessed overall survival and recurrence-free survival....

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Source

Identifiers

PMID: 24990617
DOI: 10.1093/carcin/bgu142

Genes

XPC
ERCC1
XPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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