Article
The Differential Expression of Core Genes in Nucleotide Excision Repair Pathway Indicates Colorectal Carcinogenesis and Prognosis.
BioMed research international - 1 Jan 2018
Liu Jingwei, Li Hao, Sun Liping, Feng Xue, Wang Zhenning, Yuan Yuan, Xing Chengzhong
Abstract excerpt
BACKGROUND: Nucleotide excision repair (NER) plays a critical role in maintaining genome integrity. This study aimed to investigate the expression of NER genes and their associations with colorectal cancer (CRC) development. METHOD: Expressions of NER genes in CRC and normal tissues were analysed by ONCOMINE. The Cancer Genome Atlas (TCGA) data were downloaded to explore relationship of NER expression with...
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