Article
Genetic variability of ERCC1 genes in NER pathway influences the treatment outcome of gastric cancer.
International journal of clinical and experimental pathology - 1 Jan 2015
Bai Yu, Wang Lei, Li Guangjun, Fang Xiangjie, Li Yan, Yang Shujuan
Abstract excerpt
We conducted a prospective study to analyze whether six SNPs in ERCC1 gene could serve as potential biomarkers for prognosis of gastric cancer. Between January 2010 and December 2012, 270 patients with pathologically proven gastric cancer and receiving platinum-based chemotherapy were recruited in our study. Genotyping of the ERCC1 rs11615, rs2298881, rs3212955, rs3212961, rs3212986 and were carried out...
