Association of nucleotide excision repair pathway gene polymorphisms with gastric cancer and atrophic gastritis risks.

doi:10.18632/oncotarget.6853

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Article

Association of nucleotide excision repair pathway gene polymorphisms with gastric cancer and atrophic gastritis risks.

Oncotarget - 9 Feb 2016

Liu Jingwei, Sun Liping, Xu Qian, Tu Huakang, He Caiyun, Xing Chengzhong, Yuan Yuan

Abstract excerpt

Polymorphisms of NER genes could change NER ability, thereby altering individual susceptibility to GC. We systematically analyzed 39 SNPs of 8 key genes of NER pathway in 2686 subjects including 898 gastric cancer (GC), 851 atrophic gastritis (AG) and 937 controls (CON) in northern Chinese. SNP genotyping were performed using Sequenom MassARRAY platform. The results demonstrated that DDB2 rs830083 GG genotype was...

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PMID: 26760766
DOI: 10.18632/oncotarget.6853
PMCID: PMC4872762

Genes

DDB2
XPC
XPA

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