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Article

Genetic variability of genes in NER pathway influences the treatment outcome of gastric cancer.

International journal of clinical and experimental pathology - 1 Jan 2015

Xue Ming-Hui, Li Guang-Yan, Wu Xin-Jun, Zhang Chao-Xian, Zhang Cai-Feng, Zhu Kong-Xi

Abstract excerpt

We performed a study to investigate the role of ERCC1, ERCC2, ERCC5, XPA and XPC polymorphisms from perspective of the whole NER pathway in the prognosis of gastric cancer. A total of 410 gastric cancer patients were recruited between January 2010 and December 2011. Restriction fragment length polymorphism-polymerase chain reaction (RFLP-PCR) was used to analyze genotypes of ERCC1 rs11615 and rs3212986, ERCC2...

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Source

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Identifiers

PMID: 26191265
PMCID: PMC4503136

Genes

ERCC1
ERCC2
ERCC5
XPA
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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