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Article

Structure and Function of Cross-class Complexes of G Protein-coupled Secretin and Angiotensin 1a Receptors.

The Journal of biological chemistry - 12 Aug 2016

Harikumar Kaleeckal G, Augustine Mary Lou, Lee Leo T O, Chow Billy K C, Miller Laurence J

Abstract excerpt

Complexes of secretin (SecR) and angiotensin 1a (Atr1a) receptors have been proposed to be functionally important in osmoregulation, providing an explanation for overlapping and interdependent functions of hormones that bind and activate different classes of GPCRs. However, the nature of these cross-class complexes has not been well characterized and their signaling properties have not been systematically...

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Identifiers

PMID: 27330080
DOI: 10.1074/jbc.M116.730754
PMCID: PMC5016131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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