Article
Cross-inhibition of angiotensin AT1 receptors supports the concept of receptor oligomerization.
Neurochemistry international - 1 Oct 2007
Karip Eszter, Turu Gábor, Süpeki Katinka, Szidonya László, Hunyady László
Abstract excerpt
G protein-coupled receptors are cell surface receptors that mediate the effects of extracellular signals in the endocrine/paracrine and sensory systems. Experimental evidence is accumulating, which suggest that these receptors form dimers or higher order oligomers. The functional relevance of G protein-coupled receptor dimerization or oligomerization has been raised in a number of different processes, including...
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