Apolipoprotein E ε4 does not affect cognitive performance in patients with Parkinson's disease.

doi:10.1016/j.parkreldis.2016.04.013

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Apolipoprotein E ε4 does not affect cognitive performance in patients with Parkinson's disease.

Parkinsonism & related disorders - 1 Aug 2016

Mengel David, Dams Judith, Ziemek Jannis, Becker Julian, Balzer-Geldsetzer Monika, Hilker Rüdiger, Baudrexel Simon, Kalbe Elke, Schmidt Nele, Witt Karsten, Liepelt-Scarfone Inga, Gräber Susanne, Petrelli Annette, Neuser Petra, Schulte Claudia, Linse Katharina, Storch Alexander, Wittchen Hans-Ulrich, Riedel Oliver, Mollenhauer Brit, Ebentheuer Jens, Trenkwalder Claudia, Klockgether Thomas, Spottke Annika, Wüllner Ullrich, Schulz Jörg B, Reetz Kathrin, Heber Ines Ann, Ramirez Alfredo, Dodel Richard

Abstract excerpt

INTRODUCTION: Cognitive impairment is a common and disabling non-motor symptom in Parkinson's disease (PD). The apolipoprotein E (APOE) allele ε4 is a known risk factor for Alzheimer's disease and has also been suggested to be a risk factor for dementia in PD and even a predictor of impairment in certain cognitive domains. METHODS: A total of 447 PD patients (PD patients without cognitive impairment: n = 187; PD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Apolipoprotein E4

Share to Cohort Studies

Share to DNA Mutational Analysis

Share to APOE gene

Share to Genotype

Share to Parkinson Disease

Source

Open in PubMed

Identifiers

PMID: 27321987
DOI: 10.1016/j.parkreldis.2016.04.013

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E ε4 does not affect cognitive performance in patients with Parkinson's disease.PMID 27321987Read ↗

Association analyses of apolipoprotein E genotypes and cognitive performance in patients with Parkinson's disease.Semantic proximity Read ↗

Association analyses of Apolipoprotein E genotypes and cognitive performance in patients with Parkinson’s diseaseSemantic proximity Read ↗

The impact of Apolipoprotein E alleles on cognitive performance in patients with Parkinson's disease.Semantic proximity Read ↗

Impact of the apolipoprotein E ε4 allele on early Parkinson's disease progression.Semantic proximity Read ↗

Absence of the apolipoprotein E epsilon4 allele is associated with working memory impairment in Parkinson's disease.Semantic proximity Read ↗

Clinical and neurochemical correlates of the APOE genotype in early-stage Parkinson's disease.Semantic proximity Read ↗

Cognitive, neuropsychiatric, and motor features associated with apolipoprotein E ε4 allele in a sample of Bulgarian patients with late-onset Parkinson's disease.Semantic proximity Read ↗

Apolipoprotein E genotypes and amyloid burden associated with cognitive decline in non-demented Parkinson's disease patients: A preliminary analysis.Semantic proximity Read ↗

A large study reveals no association between APOE and Parkinson's disease.Semantic proximity Read ↗

APOE E4 is associated with cognitive decline but not with disease risk or age of onset in Nigerians with Parkinson’s diseaseSemantic proximity Read ↗

Lack of association between apolipoprotein E genotypes and cognitive performance in the non-demented elderly.Semantic proximity Read ↗

APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.