Apolipoprotein E ε4 does not affect cognitive performance in patients with Parkinson's disease.

doi:10.1016/j.parkreldis.2016.04.013

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Article

Apolipoprotein E ε4 does not affect cognitive performance in patients with Parkinson's disease.

Parkinsonism & related disorders - 1 Aug 2016

Mengel David, Dams Judith, Ziemek Jannis, Becker Julian, Balzer-Geldsetzer Monika, Hilker Rüdiger, Baudrexel Simon, Kalbe Elke, Schmidt Nele, Witt Karsten, Liepelt-Scarfone Inga, Gräber Susanne, Petrelli Annette, Neuser Petra, Schulte Claudia, Linse Katharina, Storch Alexander, Wittchen Hans-Ulrich, Riedel Oliver, Mollenhauer Brit, Ebentheuer Jens, Trenkwalder Claudia, Klockgether Thomas, Spottke Annika, Wüllner Ullrich, Schulz Jörg B, Reetz Kathrin, Heber Ines Ann, Ramirez Alfredo, Dodel Richard

Abstract excerpt

INTRODUCTION: Cognitive impairment is a common and disabling non-motor symptom in Parkinson's disease (PD). The apolipoprotein E (APOE) allele ε4 is a known risk factor for Alzheimer's disease and has also been suggested to be a risk factor for dementia in PD and even a predictor of impairment in...

Topics

Adult
Aged
Aged, 80 and over
Apolipoprotein E4
Cognition Disorders
Cohort Studies
DNA Mutational Analysis
Female
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Middle Aged

Neuropsychological Tests

Parkinson Disease

Source

Open in PubMed

Identifiers

PMID: 27321987
DOI: 10.1016/j.parkreldis.2016.04.013

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-27321987-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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