Article
Cognitive, neuropsychiatric, and motor features associated with apolipoprotein E ε4 allele in a sample of Bulgarian patients with late-onset Parkinson's disease.
American journal of Alzheimer's disease and other dementias - 1 Nov 2014
Pavlova Radka, Mehrabian Shima, Petrova Maria, Skelina Silvia, Mihova Kalina, Jordanova Albena, Mitev Vanio, Traykov Latchezar
Abstract excerpt
OBJECTIVE: To evaluate the role of apolipoprotein E (APOE) ε4 allele on cognitive, neuropsychiatric, and motor features in a sample of Bulgarian patients with late-onset Parkinson's disease (LOPD, age at onset > 55 years). METHODS: A total of 16 patients with LOPD having APOE ε3/ε4 genotype were compared to 30 patients with LOPD having APOE ε3/ε3 genotype and 20 healthy control individuals. Detailed cognitive...
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