Article
The impact of Apolipoprotein E alleles on cognitive performance in patients with Parkinson's disease.
Neurologia i neurochirurgia polska - 1 Aug 2018
Pierzchlińska Anna, Białecka Monika, Kurzawski Mateusz, Sławek Jarosław
Abstract excerpt
Apolipoprotein E (ApoE) is a vital component of several lipoproteins and plays a major role in lipid metabolism. APOE gene comprises of three alleles determined by two single nucleotide polymorphisms (rs429358 and rs7412) resulting in the protein isoforms, among which ApoE4 is a confirmed risk factor for Alzheimer's Disease. However, the impact of APOE genotypes on Parkinson's Disease Dementia (PDD) is still...
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