Article
A large study reveals no association between APOE and Parkinson's disease.
Neurobiology of disease - 1 May 2012
Federoff Monica, Jimenez-Rolando Belen, Nalls Michael A, Singleton Andrew B
Abstract excerpt
BACKGROUND: Research focusing on the role of APOE in Parkinson's disease (PD) has been largely inconclusive, creating a broad discrepancy in association studies. OBJECTIVE: To elucidate the role of APOE alleles in PD risk by studying a large sample size and controlling for population substructure. PATIENTS AND METHODS: In total, 3465 case and control samples were genotyped, obtained from the NINDS Neurogenetics...
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