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Article

Association analyses of apolipoprotein E genotypes and cognitive performance in patients with Parkinson's disease.

European journal of medical research - 16 Jun 2024

Zhu Shi-Guo, Chen Zhu-Ling, Xiao Ke, Wang Zi-Wei, Lu Wen-Bin, Liu Rong-Pei, Huang Shi-Shi, Zhu Jian-Hong, Zhang Xiong, Wang Jian-Yong

Abstract excerpt

BACKGROUND: Cognitive impairment is a common non-motor symptom of Parkinson's disease (PD). The apolipoprotein E (APOE) ε4 genotype increases the risk of Alzheimer's disease (AD). However, the effect of APOEε4 on cognitive function of PD patients remains unclear. In this study, we aimed to understand whether and how carrying APOEε4 affects cognitive performance in patients with early-stage and advanced PD....

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Identifiers

PMID: 38880878
DOI: 10.1186/s40001-024-01924-2
PMCID: PMC11181540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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