Article
Lack of association between apolipoprotein E genotypes and cognitive performance in the non-demented elderly.
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society - 1 Mar 2014
Quintas Juliana Lima, Souza Vinícius Carolino, Henriques Adriane Dallanora, Machado-Silva Wilcelly, Toledo Juliana Oliveira, Córdova Cláudio, Moraes Clayton Franco, Camargos Einstein Francisco, Nóbrega Otávio Toledo
Abstract excerpt
AIM: The ε4 alelle of the apolipoprotein E gene is known to be a key genetic risk factor for Alzheimer's disease and possibly for other neurological disorders. Some evidence in the literature indicates that the ε4 allele interferes with human cognition independently of chronological age and diagnosis of Alzheimer's disease. The present study investigated the correlation of allelic variants of apolipoprotein E...
Topics
- Aged
- Apolipoproteins E
- Attention
- Brazil
- Cognition
- Cross-Sectional Studies
- Executive Function
- Female
- Genotype
- Geriatric Assessment
