Absence of the apolipoprotein E epsilon4 allele is associated with working memory impairment in Parkinson's disease.

doi:10.1016/j.jns.2006.05.032

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Article

Absence of the apolipoprotein E epsilon4 allele is associated with working memory impairment in Parkinson's disease.

Journal of the neurological sciences - 25 Oct 2006

Tröster Alexander I, Fields Julie A, Paolo Anthony M, Koller William C

Abstract excerpt

The apolipoprotein E (APOE) epsilon4 allele has been associated with an increased risk of Alzheimer's disease (AD) and weaker episodic memory among elderly. Although this APOE allele has been linked to earlier onset of Parkinson's disease (PD), an association with dementia in PD has been only inc...

Topics

Aged
Analysis of Variance
Apolipoprotein E4
Female
Gene Frequency
Genotype
Humans
Male
Memory Disorders
Memory, Short-Term
Middle Aged
Neuropsychological Tests
Parkinson Disease

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