Article
Absence of the apolipoprotein E epsilon4 allele is associated with working memory impairment in Parkinson's disease.
Journal of the neurological sciences - 25 Oct 2006
Tröster Alexander I, Fields Julie A, Paolo Anthony M, Koller William C
Abstract excerpt
The apolipoprotein E (APOE) epsilon4 allele has been associated with an increased risk of Alzheimer's disease (AD) and weaker episodic memory among elderly. Although this APOE allele has been linked to earlier onset of Parkinson's disease (PD), an association with dementia in PD has been only inconsistently demonstrated. Given the heterogeneity of cognitive impairment patterns in PD, this study sought to...
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