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Clinical and neurochemical correlates of the APOE genotype in early-stage Parkinson's disease.

Neurobiology of aging - 1 Nov 2023

Zenuni Henri, Bovenzi Roberta, Bissacco Jacopo, Grillo Piergiorgio, Simonetta Clara, Mascioli Davide, Pieri Massimo, Bernardini Segio, Sancesario Giulia Maria, Stefani Alessandro, Mercuri Nicola Biagio, Schirinzi Tommaso

Abstract excerpt

Emerging evidence indicates that apolipoprotein E (APOE) genotype may influence Parkinson's disease (PD) course, although clinical and neurochemical correlates have not been completely established. This study aimed to determine the associations of APOE genotypes (ε4 vs. non-ε4) with cerebrospinal fluid (CSF) neurodegeneration biomarkers and clinical parameters in early-stage PD patients. One hundred and...

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PMID: 37572524
DOI: 10.1016/j.neurobiolaging.2023.07.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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