Article
Covariance Association Test (CVAT) Identifies Genetic Markers Associated with Schizophrenia in Functionally Associated Biological Processes.
Genetics - 1 Aug 2016
Rohde Palle Duun, Demontis Ditte, Cuyabano Beatriz Castro Dias, Børglum Anders D, Sørensen Peter
Abstract excerpt
Schizophrenia is a psychiatric disorder with large personal and social costs, and understanding the genetic etiology is important. Such knowledge can be obtained by testing the association between a disease phenotype and individual genetic markers; however, such single-marker methods have limited power to detect genetic markers with small effects. Instead, aggregating genetic markers based on biological...
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