Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DRD3 Ser9Gly Polymorphism Predicted Metabolic Change in Drug-Naive Patients With Bipolar II Disorder.

Medicine - 1 Jun 2016

Chang Ting-Ting, Chen Shiou-Lan, Chang Yun-Hsuan, Chen Po-See, Chu Chun-Hsien, Chen Shih-Heng, Huang San-Yuan, Tzeng Nian-Sheng, Wang Liang-Jen, Wang Tzu-Yun, Li Chia-Ling, Chung Yi-Lun, Hsieh Tsai-Hsin, Lee I-Hui, Chen Kao-Ching, Yang Yen-Kuang, Hong Jau-Shyong, Lu Ru-Band, Lee Sheng-Yu

Abstract excerpt

Patients with bipolar II disorder (BDII) have a higher prevalence rate of metabolic disturbance. Whether BDII itself, in addition to its current standard treatment, is a risk factor for metabolic syndrome warrants additional study. The dopamine receptor D3 (DRD3) gene, one of the candidate genes for BDII, is also involved in the dopaminergic system. We investigated whether it is related to changes in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

Share to Double-Blind Method

Share to Gene Frequency

Share to Metabolic Syndrome

Share to Receptors, Dopamine D3

Share to Valproic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 27310943
DOI: 10.1097/MD.0000000000003488
PMCID: PMC4998429

Genes

DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DRD3 Ser9Gly Polymorphism Predicted Metabolic Change in Drug-Naive Patients With Bipolar II Disorder.PMID 27310943Read ↗

The COMT and DRD3 genes interacted in bipolar I but not bipolar II disorder.Semantic proximity Read ↗

C825T polymorphism of the GNB3 gene on valproate-related metabolic abnormalities in bipolar disorder patients.Semantic proximity Read ↗

A longitudinal study of the association between the GNB3 C825T polymorphism and metabolic disturbance in bipolar II patients treated with valproate.Semantic proximity Read ↗

The GNB3 C825T polymorphism as a pharmacogenetic marker in the treatment of hypertension, obesity, and depression.Semantic proximity Read ↗

The Gender-Specific Association of DRD2 Polymorphism with Metabolic Syndrome in Patients with Schizophrenia.Semantic proximity Read ↗

Dopamine D3 receptor Ser9Gly variant is associated with impulse control disorders in Parkinson's disease patients.Semantic proximity Read ↗

Variation in GNB3 predicts response and adverse reactions to antidepressants.Semantic proximity Read ↗

The functional DRD3 Ser9Gly polymorphism (rs6280) is pleiotropic, affecting reward as well as movement.Semantic proximity Read ↗

Metabolic syndrome and related variables, insulin resistance, leptin levels, and PPAR-γ2 and leptin gene polymorphisms in a pedigree of subjects with bipolar disorder.Semantic proximity Read ↗

Effects of the dopamine D3 receptor (DRD3) gene polymorphisms on risperidone response: a pharmacogenetic study.Semantic proximity Read ↗

Relaxin polymorphisms associated with metabolic disturbance in patients treated with antipsychotics.Semantic proximity Read ↗

The DRD2 rs1800497 polymorphism increase the risk of mood disorder: evidence from an update meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.