Article
Dopamine D3 receptor Ser9Gly variant is associated with impulse control disorders in Parkinson's disease patients.
Parkinsonism & related disorders - 1 Sept 2016
Krishnamoorthy Soumya, Rajan Roopa, Banerjee Moinak, Kumar Hardeep, Sarma Gangadhara, Krishnan Syam, Sarma Sankara, Kishore Asha
Abstract excerpt
INTRODUCTION: Impulse control disorders (ICD) are reported to occur at variable frequencies in different ethnic groups. Genetic vulnerability is suspected to underlie the individual risk for ICD. We investigated whether the allelic variants of dopamine (DRD3), glutamate (GRIN2B) and serotonin (HTR2A) receptors are linked to ICD in Indian Parkinson's disease (PD) patients. METHODS: We conducted a prospective,...
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