Article
The Gender-Specific Association of DRD2 Polymorphism with Metabolic Syndrome in Patients with Schizophrenia.
Genes - 23 Jul 2022
Paderina Diana Z, Boiko Anastasiia S, Pozhidaev Ivan V, Mednova Irina A, Goncharova Anastasia A, Bocharova Anna V, Fedorenko Olga Yu, Kornetova Elena G, Semke Arkadiy V, Bokhan Nikolay A, Loonen Anton J M, Ivanova Svetlana A
Abstract excerpt
BACKGROUND: Metabolic syndrome is widespread in patients with schizophrenia receiving long-term antipsychotic therapy. Dopamine D2 receptors play an important role in mediating both the therapeutic actions of antipsychotics and their side effects. The present study examined the association of two polymorphisms of the DRD2 gene with metabolic syndrome in patients with schizophrenia. METHODS: We examined 517...
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