Dopamine receptor D2 (DRD2) TaqIA gene polymorphism and acute risperidone-induced changes in body weight, plasma glucose and lipid profile.

doi:10.1016/j.schres.2025.03.005

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Article

Dopamine receptor D2 (DRD2) TaqIA gene polymorphism and acute risperidone-induced changes in body weight, plasma glucose and lipid profile.

Schizophrenia research - 1 Mar 2025

Olasore Holiness S A, Faleti Joseph O, Afe Taiwo O, Murtala Abdullahi A, Olawale Matthew O, Awesu Abdur-Rasheed B, Igwo-Ezikpe Miriam N, Magbagbeola Olubunmi A, Olashore Anthony A

Abstract excerpt

There are indications that the transient blockade of the dopamine receptor D2 (DRD2) by atypical antipsychotics such as risperidone is related to their metabolic side effects. We, therefore, examined the relationship between TaqIA polymorphism of the DRD2 gene and acute risperidone-induced metabolic changes. We recruited 153 newly diagnosed patients with psychotic disorders (71 males and 82 females) from the...

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Topics

Humans
Male
Female
Receptors, Dopamine D2
Risperidone
Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Blood Glucose

Antipsychotic Agents

Young Adult

Body Weight

Middle Aged

Genotype

Polymorphism, Genetic

Lipids

Psychotic Disorders

Nigeria

Adolescent

Gene Frequency

Source

Open in PubMed

Identifiers

PMID: 40073616
DOI: 10.1016/j.schres.2025.03.005

Genes

DRD2
TG

Provenance

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