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Article

C825T polymorphism of the GNB3 gene on valproate-related metabolic abnormalities in bipolar disorder patients.

Journal of clinical psychopharmacology - 1 Oct 2010

Chang Hui Hua, Gean Po Wu, Chou Chen Hsi, Yang Yen Kuang, Tsai Hsin Chun, Lu Ru Band, Chen Po See

Abstract excerpt

BACKGROUND: Valproate (VPA) is a mood stabilizer for treating patients with bipolar disorder (BD). It may cause metabolic abnormalities in certain bipolar patients. However, the genetic factors that influence the susceptibility remain unclear. Genetic polymorphism of the G-protein β3 subunit (GNB3) is reported to be associated with metabolic phenotypes. In the current study, we investigated the possible...

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Source

Identifiers

PMID: 20814328
DOI: 10.1097/JCP.0b013e3181f03f50

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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C825T polymorphism of the GNB3 gene on valproate-related metabolic abnormalities in bipolar disorder patients.PMID 20814328Read ↗

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