Article
Mycobacterium tuberculosis genotypic diversity in pyrazinamide-resistant isolates of Iran.
Microbial drug resistance (Larchmont, N.Y.) - 1 Dec 2009
Doustdar Farahnoosh, Khosravi Azar Dokht, Farnia Parissa
Abstract excerpt
Pyrazinamide (PZA) is an important first-line drug used for the short-course treatment of tuberculosis in combination with isoniazid and rifampin. It has been reported that mutations in pncA gene correlate well with PZA resistance depending on the geographic area. On the other hand, different genotypes of Mycobacterium tuberculosis show different affinities to acquire resistance-related mutations. To determine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
