Article
[Characteristics of pncA gene in multidrug-resistant Mycobacterium tuberculosis isolates and its correlation with drug resistance to pyrazinamide].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 May 2012
Hong Chuang-Yue, Wang Feng, Gui Jing, Liu Xiao-li
Abstract excerpt
OBJECTIVE: To understand the characteristics of pncA gene in multidrug-resistant Mycobacterium tuberculosis isolates and its correlation with drug resistance to pyrazinamide. METHODS: A total of 127 clinical isolates of multidrug-resistant mycobacterium tuberculosis were collected from Shenzhen from year 2007 to 2009. PZA susceptibility was determined by the BACTEC MGIT 960 PZA method. Pyrazinamidase (PZase)...
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