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Article

Depletion of Myostatin b Promotes Somatic Growth and Lipid Metabolism in Zebrafish

4 Jul 2016

Abstract excerpt

Myostatin (MSTN) is a negative regulator of myogenesis in vertebrates. Depletion of mstn resulted in elevated muscle growth in several animal species. However, the report on the complete ablation of mstn in teleost fish has not yet become available. In this study, two independent mstnb-deficient mutant lines in zebrafish were generated with the TALENs technique. In the mstnb-deficient zebrafish, enhanced muscle...

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Adipose Tissue and Metabolism
Mesenchymal stem cell research
Muscle Physiology and Disorders

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27458428
DOI: 10.3389/fendo.2016.00088

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