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Article

Genome-Wide Association Study in Immunocompetent Patients with Delayed Hypersensitivity to Sulfonamide Antimicrobials.

PloS one - 1 Jan 2016

Reinhart Jennifer M, Motsinger-Reif Alison, Dickey Allison, Yale Steven, Trepanier Lauren A

Abstract excerpt

BACKGROUND: Hypersensitivity (HS) reactions to sulfonamide antibiotics occur uncommonly, but with potentially severe clinical manifestations. A familial predisposition to sulfonamide HS is suspected, but robust predictive genetic risk factors have yet to be identified. Strongly linked genetic polymorphisms have been used clinically as screening tests for other HS reactions prior to administration of high-risk...

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Identifiers

PMID: 27272151
DOI: 10.1371/journal.pone.0156000
PMCID: PMC4896425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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