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Article

Genetic basis of hypersensitivity reactions to nonsteroidal anti-inflammatory drugs

13 Jun 2015

Abstract excerpt

PURPOSE OF REVIEW: NSAIDs are the main triggers of hypersensitivity reactions to drugs. However, the full genetic and molecular basis of these reactions has yet to be uncovered. In this article, we have summarized research from recent years into the effects of genetic variants on the different clinical entities induced by NSAID hypersensitivity, focusing on prostaglandin and leukotriene-related genes as well as...

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Share to Asthma and respiratory diseases
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PMID: 26110677
DOI: 10.1097/aci.0000000000000178

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