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Article

Update on the Genetic Basis of Drug Hypersensitivity Reactions.

Journal of investigational allergology & clinical immunology - 1 Jan 2000

Jurado-Escobar R, Perkins J R, García-Martín E, Isidoro-García M, Doña I, Torres M J, Cornejo-García J A

Abstract excerpt

Drug hypersensitivity reactions (DHRs) are unpredictable, complex responses to medicines in predisposed individuals. They represent a major health problem owing to the number of patients affected and the severity of the clinical conditions they can induce. In addition to environmental factors, the underlying mechanisms of DHRs are also influenced by genetic factors, although considerable gaps remain in our...

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Source

Identifiers

PMID: 29199960
DOI: 10.18176/jiaci.0199

Genes

ALOX5
CYSLTR1
LGALS3
NOD2
PTGDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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