Article
Genetics of rheumatoid arthritis.
Best practice & research. Clinical rheumatology - 1 Dec 2024
Sharma Seema D, Leung Shek H, Viatte Sebastien
Abstract excerpt
In the past four decades, a plethora of genetic association studies have been carried out in cohorts of patients with rheumatoid arthritis. These studies have highlighted key aspects of disease pathogenesis and suggested causal mechanisms. In this review, we discuss major advances in our understanding of the genetic architecture of rheumatoid arthritis susceptibility, severity and treatment response and explain...
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