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Article

8q24 genetic variation and comprehensive haplotypes altering familial risk of prostate cancer.

Nature communications - 23 Mar 2020

Dupont William D, Breyer Joan P, Plummer W Dale, Chang Sam S, Cookson Michael S, Smith Joseph A, Blue Elizabeth E, Bamshad Michael J, Smith Jeffrey R

Abstract excerpt

The 8q24 genomic locus is tied to the origin of numerous cancers. We investigate its contribution to hereditary prostate cancer (HPC) in independent study populations of the Nashville Familial Prostate Cancer Study and International Consortium for Prostate Cancer Genetics (combined: 2,836 HPC cases, 2,206 controls of European ancestry). Here we report 433 variants concordantly associated with HPC in both study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32251286
DOI: 10.1038/s41467-020-15122-1
PMCID: PMC7089954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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