Article
Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease.
Human genetics - 1 Mar 2014
Teerlink Craig C, Thibodeau Stephen N, McDonnell Shannon K, Schaid Daniel J, Rinckleb Antje, Maier Christiane, Vogel Walther, Cancel-Tassin Geraldine, Egrot Christophe, Cussenot Olivier, Foulkes William D, Giles Graham G, Hopper John L, Severi Gianluca, Eeles Ros, Easton Douglas, Kote-Jarai Zsofia, Guy Michelle, Cooney Kathleen A, Ray Anna M, Zuhlke Kimberly A, Lange Ethan M, Fitzgerald Liesel M, Stanford Janet L, Ostrander Elaine A, Wiley Kathleen E, Isaacs Sarah D, Walsh Patrick C, Isaacs William B, Wahlfors Tiina, Tammela Teuvo, Schleutker Johanna, Wiklund Fredrik, Grönberg Henrik, Emanuelsson Monica, Carpten John, Bailey-Wilson Joan, Whittemore Alice S, Oakley-Girvan Ingrid, Hsieh Chih-Lin, Catalona William J, Zheng S Lilly, Jin Guangfu, Lu Lingyi, Xu Jianfeng, Camp Nicola J, Cannon-Albright Lisa A
Abstract excerpt
Previous GWAS studies have reported significant associations between various common SNPs and prostate cancer risk using cases unselected for family history. How these variants influence risk in familial prostate cancer is not well studied. Here, we analyzed 25 previously reported SNPs across 14 loci from prior prostate cancer GWAS. The International Consortium for Prostate Cancer Genetics (ICPCG) previously...
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