Article
Genome stability versus transcript diversity.
DNA repair - 1 Aug 2016
Magnuson Brian, Bedi Karan, Ljungman Mats
Abstract excerpt
Our genome is protected from the introduction of mutations by high fidelity replication and an extensive network of DNA damage response and repair mechanisms. However, the expression of our genome, via RNA and protein synthesis, allows for more diversity in translating genetic information. In addition, the splicing process has become less stringent over evolutionary time allowing for a substantial increase in the...
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