Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative mRNA processing sites decrease genetic variability while increasing functional diversity.

Transcription - 1 Jan 2018

Auboeuf Didier

Abstract excerpt

Recent large-scale RNA sequencing efforts have revealed the extensive diversity of mRNA molecules produced from most eukaryotic coding genes, which arises from the usage of alternative, cryptic or non-canonical splicing and intronic polyadenylation sites. The prevailing view regarding the tremendous diversity of coding gene transcripts is that mRNA processing is a flexible and more-or-less noisy process leading...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to DNA
Share to Genomic Instability

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Introns

Share to Protein Biosynthesis

Share to Proteins

Share to RNA, Messenger

Share to Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 29099315
DOI: 10.1080/21541264.2017.1373891
PMCID: PMC5834221

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative mRNA processing sites decrease genetic variability while increasing functional diversity.PMID 29099315Read ↗

<i>SpliceImpactR</i> maps alternative RNA processing events driving protein functional diversitySemantic proximity Read ↗

Alternative splicing as a source of phenotypic diversity.Semantic proximity Read ↗

Mechanisms and Regulation of Alternative Pre-mRNA Splicing.Semantic proximity Read ↗

Function of alternative splicing.Semantic proximity Read ↗

Genomics of alternative splicing: evolution, development and pathophysiology.Semantic proximity Read ↗

The splice of life: how alternative splicing shapes regulatory and phenotypic evolution.Semantic proximity Read ↗

The generation of protein isoform diversity by alternative RNA splicing.Semantic proximity Read ↗

Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing.Semantic proximity Read ↗

RNA variation as the driver of genomic efficiency and phenotypic complexity.Semantic proximity Read ↗

A genomic view of alternative splicing.Semantic proximity Read ↗

Diversity and evolution of spliceosomal systems.Semantic proximity Read ↗

Two sides of the same medal: Noncoding mutations reveal new pathological mechanisms and insights into the regulation of gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.