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Article

RNA Polymerase III Advances: Structural and tRNA Functional Views.

Trends in biochemical sciences - 1 Jun 2016

Arimbasseri Aneeshkumar G, Maraia Richard J

Abstract excerpt

RNA synthesis in eukaryotes is divided among three RNA polymerases (RNAPs). RNAP III transcribes hundreds of tRNA genes and fewer additional short RNA genes. We survey recent work on transcription by RNAP III including an atomic structure, mechanisms of action, interactions with chromatin and retroposons, and a conserved link between its activity and a tRNA modification that enhances mRNA decoding. Other new work...

Topics

Autoimmunity
Chromatin
Codon
Humans
Mutation
Neoplasms
Oxidative Stress
Pluripotent Stem Cells
Protein Biosynthesis
RNA Polymerase III
RNA, Messenger
RNA, Transfer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Repressor Proteins

Retroelements

Transcription Factors

Transcription, Genetic

Source

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Identifiers

PMID: 27068803
DOI: 10.1016/j.tibs.2016.03.003
PMCID: PMC4884153

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