Article
Environmental influences on RNA processing: Biochemical, molecular and genetic regulators of cellular response.
Wiley interdisciplinary reviews. RNA - 1 Jan 2019
Pai Athma A, Luca Francesca
Abstract excerpt
RNA processing has emerged as a key mechanistic step in the regulation of the cellular response to environmental perturbation. Recent work has uncovered extensive remodeling of transcriptome composition upon environmental perturbation and linked the impacts of this molecular plasticity to health and disease outcomes. These isoform changes and their underlying mechanisms are varied-involving alternative sites of...
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