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Article

Functional validation of tensin2 SH2-PTB domain by CRISPR/Cas9-mediated genome editing.

The Journal of veterinary medical science - 1 Oct 2016

Marusugi Kiyoma, Nakano Kenta, Sasaki Hayato, Kimura Junpei, Yanobu-Takanashi Rieko, Okamura Tadashi, Sasaki Nobuya

Abstract excerpt

Podocytes are terminally differentiated and highly specialized cells in the glomerulus, and they form a crucial component of the glomerular filtration barrier. The ICGN mouse is a model of glomerular dysfunction that shows gross morphological changes in the podocyte foot process, accompanied by proteinuria. Previously, we demonstrated that proteinuria in ICR-derived glomerulonephritis mouse ICGN mice might be...

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Identifiers

PMID: 27246398
DOI: 10.1292/jvms.16-0205
PMCID: PMC5059368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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